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SIRT7 is activated by DNA and deacetylates histone H3 in the chromatin context

Mammalian sirtuins (SIRT1-7) are members of a highly conserved family of nicotinamide adenine dinucleotide (NAD(+))-dependent protein deacetylases that regulate many biological processes including metabolism, genome stability, and transcription. Among the seven human sirtuins, SIRT7 is the least und...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Tong, Zhen, Wang, Yi, Zhang, Xiaoyu, Kim, David D., Sadhukhan, Sushabhan, Hao, Quan, Lin, Hening
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850736/
https://ncbi.nlm.nih.gov/pubmed/26907567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b01084
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