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Seamless site-directed mutagenesis of the Saccharomyces cerevisiae genome using CRISPR-Cas9

CRISPR assisted homology directed repair enables the introduction of virtually any modification to the Saccharomyces cerevisiae genome. Of obvious interest is the marker-free and seamless introduction of point mutations. To fulfill this promise, a strategy that effects single nucleotide changes whil...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Eng
Egile Nagusiak: Biot-Pelletier, Damien, Martin, Vincent J. J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4850645/
https://ncbi.nlm.nih.gov/pubmed/27134651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-016-0028-1
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