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Using a Genetically Encoded Sensor to Identify Inhibitors of Toxoplasma gondii Ca(2+) Signaling
The life cycles of apicomplexan parasites progress in accordance with fluxes in cytosolic Ca(2+). Such fluxes are necessary for events like motility and egress from host cells. We used genetically encoded Ca(2+) indicators (GCaMPs) to develop a cell-based phenotypic screen for compounds that modulat...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4850295/ https://ncbi.nlm.nih.gov/pubmed/26933036 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.703546 |
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