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THE p75 NEUROTROPHIN RECEPTOR AUGMENTS SURVIVAL SIGNALING IN THE STRIATUM OF PRE-SYMPTOMATIC Q175(WT/HD) MICE

Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder characterized by a constellation of motor, cognitive, and psychiatric features. Striatal medium spiny neurons, one of the most affected populations, are dependent on brain-derived neurotrophic factor (BDNF) anterogradely...

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Detalhes bibliográficos
Publicado no:Neuroscience
Main Authors: WEHNER, A. B., MILEN, A. M., ALBIN, R. L., PIERCHALA, B. A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849895/
https://ncbi.nlm.nih.gov/pubmed/26947127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.02.069
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