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THE p75 NEUROTROPHIN RECEPTOR AUGMENTS SURVIVAL SIGNALING IN THE STRIATUM OF PRE-SYMPTOMATIC Q175(WT/HD) MICE
Huntington’s disease (HD) is a dominantly inherited neurodegenerative disorder characterized by a constellation of motor, cognitive, and psychiatric features. Striatal medium spiny neurons, one of the most affected populations, are dependent on brain-derived neurotrophic factor (BDNF) anterogradely...
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Publicado no: | Neuroscience |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4849895/ https://ncbi.nlm.nih.gov/pubmed/26947127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2016.02.069 |
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