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Transgenic Restoration of Urea Transporter A1 Confers Maximal Urinary Concentration in the Absence of Urea Transporter A3

Urea has a critical role in urinary concentration. Mice lacking the inner medullary collecting duct (IMCD) urea transporter A1 (UT-A1) and urea transporter A3 (UT-A3) have very low levels of urea permeability and are unable to concentrate urine. To investigate the role of UT-A1 in the concentration...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Klein, Janet D., Wang, Yanhua, Mistry, Abinash, LaRocque, Lauren M., Molina, Patrick A., Rogers, Richard T., Blount, Mitsi A., Sands, Jeff M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849813/
https://ncbi.nlm.nih.gov/pubmed/26407594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014121267
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