Mast Cell Stabilization Ameliorates Autoimmune Anti-Myeloperoxidase Glomerulonephritis

Observations in experimental murine myeloperoxidase (MPO)-ANCA-associated vasculitis (AAV) show mast cells degranulate, thus enhancing injury as well as producing immunomodulatory IL-10. Here we report that, compared with biopsy specimens from control patients, renal biopsy specimens from 44 patient...

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Détails bibliographiques
Publié dans:J Am Soc Nephrol
Auteurs principaux: Gan, Poh-Yi, O’Sullivan, Kim M., Ooi, Joshua D., Alikhan, Maliha A., Odobasic, Dragana, Summers, Shaun A., Kitching, A. Richard, Holdsworth, Stephen R.
Format: Artigo
Langue:Inglês
Publié: American Society of Nephrology 2016
Sujets:
Basic Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849811/
https://ncbi.nlm.nih.gov/pubmed/26374606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014090906
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