ANP32B deficiency impairs proliferation and suppresses tumor progression by regulating AKT phosphorylation

The acidic leucine-rich nuclear phosphoprotein 32B (ANP32B) is reported to impact normal development, with Anp32b-knockout mice exhibiting smaller size and premature aging. However, its cellular and molecular mechanisms, especially its potential roles in tumorigenesis, remain largely unclear. Here,...

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Publicat a:Cell Death Dis
Autors principals: Yang, S, Zhou, L, Reilly, P T, Shen, S-M, He, P, Zhu, X-N, Li, C-X, Wang, L-S, Mak, T W, Chen, G-Q, Yu, Y
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849165/
https://ncbi.nlm.nih.gov/pubmed/26844697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.8
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