ANP32B Deficiency Protects Mice From Lethal Influenza A Virus Challenge by Dampening the Host Immune Response

Deciphering complex virus-host interactions is crucial for pandemic preparedness. In this study, we assessed the impact of recently postulated cellular factors ANP32A and ANP32B of influenza A virus (IAV) species specificity on viral pathogenesis in a genetically modified mouse model. Infection of A...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Beck, Sebastian, Zickler, Martin, Pinho dos Reis, Vinícius, Günther, Thomas, Grundhoff, Adam, Reilly, Patrick T., Mak, Tak W., Stanelle-Bertram, Stephanie, Gabriel, Gülşah
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7083139/
https://ncbi.nlm.nih.gov/pubmed/32231671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00450
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