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Loss of Fas apoptosis inhibitory molecule leads to spontaneous obesity and hepatosteatosis
Altered hepatic lipogenesis is associated with metabolic diseases such as obesity and hepatosteatosis. Insulin resistance and compensatory hyperinsulinaemia are key drivers of these metabolic imbalances. Fas apoptosis inhibitory molecule (FAIM), a ubiquitously expressed antiapoptotic protein, functi...
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| Publié dans: | Cell Death Dis |
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| Auteurs principaux: | , , , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4849152/ https://ncbi.nlm.nih.gov/pubmed/26866272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.12 |
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