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Loss of Fas apoptosis inhibitory molecule leads to spontaneous obesity and hepatosteatosis

Altered hepatic lipogenesis is associated with metabolic diseases such as obesity and hepatosteatosis. Insulin resistance and compensatory hyperinsulinaemia are key drivers of these metabolic imbalances. Fas apoptosis inhibitory molecule (FAIM), a ubiquitously expressed antiapoptotic protein, functi...

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Détails bibliographiques
Publié dans:Cell Death Dis
Auteurs principaux: Huo, J, Ma, Y, Liu, J-J, Ho, Y S, Liu, S, Soh, L Y, Chen, S, Xu, S, Han, W, Hong, A, Lim, S C, Lam, K-P
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849152/
https://ncbi.nlm.nih.gov/pubmed/26866272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.12
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