Loss of Fas apoptosis inhibitory molecule leads to spontaneous obesity and hepatosteatosis

Altered hepatic lipogenesis is associated with metabolic diseases such as obesity and hepatosteatosis. Insulin resistance and compensatory hyperinsulinaemia are key drivers of these metabolic imbalances. Fas apoptosis inhibitory molecule (FAIM), a ubiquitously expressed antiapoptotic protein, functi...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Huo, J, Ma, Y, Liu, J-J, Ho, Y S, Liu, S, Soh, L Y, Chen, S, Xu, S, Han, W, Hong, A, Lim, S C, Lam, K-P
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849152/
https://ncbi.nlm.nih.gov/pubmed/26866272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.12
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