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Fas Apoptosis Inhibitory Molecule Expression in B Cells Is Regulated through IRF4 in a Feed-Forward Mechanism()

Fas apoptosis inhibitory molecule (FAIM) was originally cloned as an inhibitor of Fas-mediated apoptosis in B cells that has been reported to affect multiple cell types. Recently, we found that FAIM enhances CD40L-mediated signal transduction, including induction of IFN regulatory factor (IRF)4, in...

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Detalhes bibliográficos
Main Authors: Kaku, Hiroaki, Rothstein, Thomas L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587132/
https://ncbi.nlm.nih.gov/pubmed/19843941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0901988
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