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Inhibition of AKT promotes FOXO3a-dependent apoptosis in prostate cancer
Growth factor-induced activation of protein kinase-B (PKB), also known as AKT, induces pro-survival signaling and inhibits activation of pro-apoptotic signaling molecules including the Forkhead box O-3a (FOXO3a) transcription factor and caspase in transformed prostate cells in vitro. Earlier we repo...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4849149/ https://ncbi.nlm.nih.gov/pubmed/26913603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.403 |
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