Withaferin A Inhibits Prostate Carcinogenesis in a PTEN-deficient Mouse Model of Prostate Cancer()()

We recently demonstrated that AKT activation plays a role in prostate cancer progression and inhibits the pro-apoptotic function of FOXO3a and Par-4. AKT inhibition and Par-4 induction suppressed prostate cancer progression in preclinical models. Here, we investigate the chemopreventive effect of th...

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Publicat a:Neoplasia
Autors principals: Moselhy, Jim, Suman, Suman, Alghamdi, Mohammed, Chandarasekharan, Balaji, Das, Trinath P., Houda, Alatassi, Ankem, Murali, Damodaran, Chendil
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2017
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Original article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421823/
https://ncbi.nlm.nih.gov/pubmed/28494348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2017.04.005
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