Inhibition of autophagy prevents cadmium-induced prostate carcinogenesis

BACKGROUND: Cadmium, an established carcinogen, is a risk factor for prostate cancer. Induction of autophagy is a prerequisite for cadmium-induced transformation and metastasis. The ability of Psoralidin (Pso), a non-toxic, orally bioavailable compound to inhibit cadmium-induced autophagy to prevent...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Pal, Deeksha, Suman, Suman, Kolluru, Venkatesh, Sears, Sophia, Das, Trinath P, Alatassi, Houda, Ankem, Murali K, Freedman, Jonathan H, Damodaran, Chendil
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520206/
https://ncbi.nlm.nih.gov/pubmed/28588318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.143
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