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Addressing inaccuracies in BLOSUM computation improves homology search performance
BACKGROUND: BLOSUM matrices belong to the most commonly used substitution matrix series for protein homology search and sequence alignments since their publication in 1992. In 2008, Styczynski et al. discovered miscalculations in the clustering step of the matrix computation. Still, the RBLOSUM64 ma...
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| Publicado no: | BMC Bioinformatics |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4849092/ https://ncbi.nlm.nih.gov/pubmed/27122148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1060-3 |
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