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Addressing inaccuracies in BLOSUM computation improves homology search performance
BACKGROUND: BLOSUM matrices belong to the most commonly used substitution matrix series for protein homology search and sequence alignments since their publication in 1992. In 2008, Styczynski et al. discovered miscalculations in the clustering step of the matrix computation. Still, the RBLOSUM64 ma...
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| Publicat a: | BMC Bioinformatics |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4849092/ https://ncbi.nlm.nih.gov/pubmed/27122148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1060-3 |
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