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Gentle Masking of Low-Complexity Sequences Improves Homology Search

Detection of sequences that are homologous, i.e. descended from a common ancestor, is a fundamental task in computational biology. This task is confounded by low-complexity tracts (such as atatatatatat), which arise frequently and independently, causing strong similarities that are not homologies. T...

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Bibliografische gegevens
Hoofdauteur: Frith, Martin C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3242753/
https://ncbi.nlm.nih.gov/pubmed/22205972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028819
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