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SAAMBE: Webserver to Predict the Charge of Binding Free Energy Caused by Amino Acids Mutations

Predicting the effect of amino acid substitutions on protein–protein affinity (typically evaluated via the change of protein binding free energy) is important for both understanding the disease-causing mechanism of missense mutations and guiding protein engineering. In addition, researchers are also...

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Foilsithe in:Int J Mol Sci
Main Authors: Petukh, Marharyta, Dai, Luogeng, Alexov, Emil
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849003/
https://ncbi.nlm.nih.gov/pubmed/27077847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17040547
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