Deficiency of Senescence Marker Protein 30 Exacerbates Cardiac Injury after Ischemia/Reperfusion

Early myocardial reperfusion is an effective therapy but ischemia/reperfusion (I/R) causes lethal myocardial injury. The aging heart was reported to show greater cardiac damage after I/R injury than that observed in young hearts. Senescence marker protein 30 (SMP30), whose expression decreases with...

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Published in:Int J Mol Sci
Main Authors: Kadowaki, Shinpei, Shishido, Tetsuro, Sasaki, Toshiki, Sugai, Takayuki, Narumi, Taro, Honda, Yuki, Otaki, Yoichiro, Kinoshita, Daisuke, Takahashi, Tetsuya, Nishiyama, Satoshi, Takahashi, Hiroki, Arimoto, Takanori, Miyamoto, Takuya, Watanabe, Tetsu, Ishigami, Akihiko, Takeishi, Yasuchika, Kubota, Isao
Format: Artigo
Language:Inglês
Published: MDPI 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848998/
https://ncbi.nlm.nih.gov/pubmed/27077846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17040542
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