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KRAS G12V Mutation Detection by Droplet Digital PCR in Circulating Cell-Free DNA of Colorectal Cancer Patients

KRAS mutations are responsible for resistance to anti-epidermal growth factor receptor (EGFR) therapy in colorectal cancer patients. These mutations sometimes appear once treatment has started. Detection of KRAS mutations in circulating cell-free DNA in plasma (“liquid biopsy”) by droplet digital PC...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Olmedillas López, Susana, García-Olmo, Dolores C., García-Arranz, Mariano, Guadalajara, Héctor, Pastor, Carlos, García-Olmo, Damián
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848940/
https://ncbi.nlm.nih.gov/pubmed/27043547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17040484
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