Droplet digital PCR of circulating tumor cells from colorectal cancer patients can predict KRAS mutations before surgery

In colorectal cancer (CRC), KRAS mutations are a strong negative predictor for treatment with the EGFR‐targeted antibodies cetuximab and panitumumab. Since it can be difficult to obtain appropriate tumor tissues for KRAS genotyping, alternative methods are required. Circulating tumor cells (CTCs) ar...

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Опубликовано в: :Mol Oncol
Главные авторы: Denis, Jérôme Alexandre, Patroni, Alexia, Guillerm, Erell, Pépin, Dominique, Benali-Furet, Naoual, Wechsler, Janine, Manceau, Gilles, Bernard, Maguy, Coulet, Florence, Larsen, Annette K., Karoui, Mehdi, Lacorte, Jean-Marc
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
Предметы:
Research Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423194/
https://ncbi.nlm.nih.gov/pubmed/27311775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2016.05.009
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