Droplet digital PCR of circulating tumor cells from colorectal cancer patients can predict KRAS mutations before surgery

In colorectal cancer (CRC), KRAS mutations are a strong negative predictor for treatment with the EGFR‐targeted antibodies cetuximab and panitumumab. Since it can be difficult to obtain appropriate tumor tissues for KRAS genotyping, alternative methods are required. Circulating tumor cells (CTCs) ar...

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Publicado en:Mol Oncol
Autores principales: Denis, Jérôme Alexandre, Patroni, Alexia, Guillerm, Erell, Pépin, Dominique, Benali-Furet, Naoual, Wechsler, Janine, Manceau, Gilles, Bernard, Maguy, Coulet, Florence, Larsen, Annette K., Karoui, Mehdi, Lacorte, Jean-Marc
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423194/
https://ncbi.nlm.nih.gov/pubmed/27311775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2016.05.009
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