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Targeting Protein–Protein Interactions in the HIF System
Animals respond to chronic hypoxia by increasing the levels of a transcription factor known as the hypoxia‐inducible factor (HIF). HIF upregulates multiple genes, the products of which work to ameliorate the effects of limited oxygen at cellular and systemic levels. Hypoxia sensing by the HIF system...
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| Publicado no: | ChemMedChem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4848768/ https://ncbi.nlm.nih.gov/pubmed/26997519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600012 |
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