Targeting Protein–Protein Interactions in the HIF System

Animals respond to chronic hypoxia by increasing the levels of a transcription factor known as the hypoxia‐inducible factor (HIF). HIF upregulates multiple genes, the products of which work to ameliorate the effects of limited oxygen at cellular and systemic levels. Hypoxia sensing by the HIF system...

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Sparad:
Bibliografiska uppgifter
I publikationen:ChemMedChem
Huvudupphovsmän: Wilkins, Sarah E., Abboud, Martine I., Hancock, Rebecca L., Schofield, Christopher J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2016
Ämnen:
Reviews
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848768/
https://ncbi.nlm.nih.gov/pubmed/26997519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600012
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