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Targeting Protein–Protein Interactions in the HIF System
Animals respond to chronic hypoxia by increasing the levels of a transcription factor known as the hypoxia‐inducible factor (HIF). HIF upregulates multiple genes, the products of which work to ameliorate the effects of limited oxygen at cellular and systemic levels. Hypoxia sensing by the HIF system...
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出版年: | ChemMedChem |
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主要な著者: | , , , |
フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
John Wiley and Sons Inc.
2016
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4848768/ https://ncbi.nlm.nih.gov/pubmed/26997519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600012 |
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