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Targeting Protein–Protein Interactions in the HIF System

Animals respond to chronic hypoxia by increasing the levels of a transcription factor known as the hypoxia‐inducible factor (HIF). HIF upregulates multiple genes, the products of which work to ameliorate the effects of limited oxygen at cellular and systemic levels. Hypoxia sensing by the HIF system...

詳細記述

保存先:
書誌詳細
出版年:ChemMedChem
主要な著者: Wilkins, Sarah E., Abboud, Martine I., Hancock, Rebecca L., Schofield, Christopher J.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848768/
https://ncbi.nlm.nih.gov/pubmed/26997519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600012
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