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Targeting Protein–Protein Interactions in the HIF System

Animals respond to chronic hypoxia by increasing the levels of a transcription factor known as the hypoxia‐inducible factor (HIF). HIF upregulates multiple genes, the products of which work to ameliorate the effects of limited oxygen at cellular and systemic levels. Hypoxia sensing by the HIF system...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:ChemMedChem
Egile Nagusiak: Wilkins, Sarah E., Abboud, Martine I., Hancock, Rebecca L., Schofield, Christopher J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848768/
https://ncbi.nlm.nih.gov/pubmed/26997519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201600012
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