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Cyclic and Macrocyclic Peptides as Chemical Tools To Recognise Protein Surfaces and Probe Protein–Protein Interactions

Targeting protein surfaces and protein–protein interactions (PPIs) with small molecules is a frontier goal of chemical biology and provides attractive therapeutic opportunities in drug discovery. The molecular properties of protein surfaces, including their shallow features and lack of deep binding...

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Publicado en:ChemMedChem
Main Authors: Cardote, Teresa A. F., Ciulli, Alessio
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848765/
https://ncbi.nlm.nih.gov/pubmed/26563831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201500450
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