Identifying genetically driven clinical phenotypes using linear mixed models

We hypothesized that generalized linear mixed models (GLMMs), which estimate the additive genetic variance underlying phenotype variability, would facilitate rapid characterization of clinical phenotypes from an electronic health record. We evaluated 1,288 phenotypes in 29,349 subjects of European a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Mosley, Jonathan D., Witte, John S., Larkin, Emma K., Bastarache, Lisa, Shaffer, Christian M., Karnes, Jason H., Stein, C. Michael, Phillips, Elizabeth, Hebbring, Scott J., Brilliant, Murray H., Mayer, John, Ye, Zhan, Roden, Dan M., Denny, Joshua C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848547/
https://ncbi.nlm.nih.gov/pubmed/27109359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11433
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak