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Lovastatin causes FaDu hypopharyngeal carcinoma cell death via AMPK-p63-survivin signaling cascade

Statins are used widely to lower serum cholesterol and the incidence of cardiovascular diseases. Growing evidence shows that statins also exhibit beneficial effects against cancers. In this study, we investigated the molecular mechanisms involved in lovastatin-induced cell death in Fadu hypopharynge...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yen, Chia-Sheng, Chen, Jung-Chien, Chang, Yi-Fang, Hsu, Ya-Fen, Chiu, Pei-Ting, Shiue, Ching, Chuang, Yu-Fan, Ou, George, Hsu, Ming-Jen
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848532/
https://ncbi.nlm.nih.gov/pubmed/27122225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25082
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