Timcodar (VX-853) Is a Non-FKBP12 Binding Macrolide Derivative That Inhibits PPARγ and Suppresses Adipogenesis

Nutrient overload and genetic factors have led to a worldwide epidemic of obesity that is the underlying cause of diabetes, atherosclerosis, and cardiovascular disease. In this study, we used macrolide drugs such as FK506, rapamycin, and macrolide derived, timcodar (VX-853), to determine their effec...

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Detalhes bibliográficos
Publicado no:PPAR Res
Main Authors: Hinds, Terry D., John, Kezia, McBeth, Lucien, Trabbic, Christopher J., Sanchez, Edwin R.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848453/
https://ncbi.nlm.nih.gov/pubmed/27190501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/6218637
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