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RVTESTS: an efficient and comprehensive tool for rare variant association analysis using sequence data

Motivation: Next-generation sequencing technologies have enabled the large-scale assessment of the impact of rare and low-frequency genetic variants for complex human diseases. Gene-level association tests are often performed to analyze rare variants, where multiple rare variants in a gene region ar...

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Detaylı Bibliyografya
Yayımlandı:Bioinformatics
Asıl Yazarlar: Zhan, Xiaowei, Hu, Youna, Li, Bingshan, Abecasis, Goncalo R., Liu, Dajiang J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848408/
https://ncbi.nlm.nih.gov/pubmed/27153000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw079
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