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Sensor Function for Butyrophilin 3A1 in Prenyl Pyrophosphate Stimulation of Human Vγ2Vδ2 T Cells

Vγ2Vδ2 T cells play important roles in human immunity to pathogens and in cancer immunotherapy by responding to isoprenoid metabolites, such as (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate and isopentenyl pyrophosphate. The Ig superfamily protein butyrophilin (BTN)3A1 was shown to be required for...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Wang, Hong, Morita, Craig T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4848273/
https://ncbi.nlm.nih.gov/pubmed/26475929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500314
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