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Butyrophilin 3A1 Plays an Essential Role in Prenyl Pyrophosphate Stimulation of Human Vγ2Vδ2 T Cells

Most human γδ T cells express Vγ2Vδ2 TCRs and play important roles in microbial and tumor immunity. Vγ2Vδ2 T cells are stimulated by self- and foreign prenyl pyrophosphate intermediates in isoprenoid synthesis. However, little is known about the molecular basis for this stimulation. We find that a m...

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Detalhes bibliográficos
Main Authors: Wang, Hong, Henry, Olivier, Distefano, Mark D., Wang, Yen-Chih, Räikkönen, Johanna, Mönkkönen, Jukka, Tanaka, Yoshimasa, Morita, Craig T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3884521/
https://ncbi.nlm.nih.gov/pubmed/23833237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300658
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