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Vγ2Vδ2 T Cell Receptor Recognition of Prenyl Pyrophosphates is Dependent on all Complementarity Determining Regions

γδ T cells differ from αβ T cells in the antigens they recognize and their functions in immunity. While most αβ T cell receptors (TCR) recognize peptides presented by MHC class I or II, human γδ T cells expressing Vγ2Vδ2 TCRs recognize nonpeptide prenyl pyrophosphates. To define the molecular basis...

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Autori principali: Wang, Hong, Fang, Zhimei, Morita, Craig T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3069129/
https://ncbi.nlm.nih.gov/pubmed/20483784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000231
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