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Structure and substrate sequestration in the pyoluteorin type II peptidyl carrier protein PltL

Type II non-ribosomal peptide synthetases (NRPS) generate exotic amino acid derivatives that, combined with additional pathways, form many bioactive natural products. One family of type II NRPSs produce pyrrole moieties, which commonly arise from proline oxidation while tethered to a conserved, type...

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Bibliografske podrobnosti
izdano v:J Am Chem Soc
Main Authors: Jaremko, Matt J., Lee, D. John, Opella, Stanley J., Burkart, Michael D.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847951/
https://ncbi.nlm.nih.gov/pubmed/26340431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b04525
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