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Binding and pK(a) Modulation of a Polycyclic Substrate Analog in a Type II Polyketide Acyl Carrier Protein
Type II polyketide synthases are biosynthetic enzymatic pathways responsible for the production of complex aromatic natural products with important biological activities. In these systems, biosynthetic intermediates are covalently bound to a small acyl carrier protein that associates with the syntha...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3092034/ https://ncbi.nlm.nih.gov/pubmed/21268653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb200004k |
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