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An Electrostatic Funnel in the GABA-Binding Pathway
The γ-aminobutyric acid type A receptor (GABA(A)-R) is a major inhibitory neuroreceptor that is activated by the binding of GABA. The structure of the GABA(A)-R is well characterized, and many of the binding site residues have been identified. However, most of these residues are obscured behind the...
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| Pubblicato in: | PLoS Comput Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4847780/ https://ncbi.nlm.nih.gov/pubmed/27119953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004831 |
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