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An Electrostatic Funnel in the GABA-Binding Pathway

The γ-aminobutyric acid type A receptor (GABA(A)-R) is a major inhibitory neuroreceptor that is activated by the binding of GABA. The structure of the GABA(A)-R is well characterized, and many of the binding site residues have been identified. However, most of these residues are obscured behind the...

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Библиографические подробности
Опубликовано в: :PLoS Comput Biol
Главные авторы: Carpenter, Timothy S., Lightstone, Felice C.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847780/
https://ncbi.nlm.nih.gov/pubmed/27119953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004831
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