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Memory retrieval by activating engram cells in mouse models of early Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive memory decline and subsequent loss of broader cognitive functions(1). Memory decline in early stages of Alzheimer’s is mostly limited to episodic memory, for which the hippocampus (HPC) plays a crucial role(2). How...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nature
Main Authors: Roy, Dheeraj S., Arons, Autumn, Mitchell, Teryn I., Pignatelli, Michele, Ryan, Tomás J., Tonegawa, Susumu
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847731/
https://ncbi.nlm.nih.gov/pubmed/26982728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17172
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