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Memory retrieval by activating engram cells in mouse models of early Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive memory decline and subsequent loss of broader cognitive functions(1). Memory decline in early stages of Alzheimer’s is mostly limited to episodic memory, for which the hippocampus (HPC) plays a crucial role(2). How...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Roy, Dheeraj S., Arons, Autumn, Mitchell, Teryn I., Pignatelli, Michele, Ryan, Tomás J., Tonegawa, Susumu
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847731/
https://ncbi.nlm.nih.gov/pubmed/26982728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17172
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