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Memory retrieval by activating engram cells in mouse models of early Alzheimer’s disease

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive memory decline and subsequent loss of broader cognitive functions(1). Memory decline in early stages of Alzheimer’s is mostly limited to episodic memory, for which the hippocampus (HPC) plays a crucial role(2). How...

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Bibliografiska uppgifter
I publikationen:Nature
Huvudupphovsmän: Roy, Dheeraj S., Arons, Autumn, Mitchell, Teryn I., Pignatelli, Michele, Ryan, Tomás J., Tonegawa, Susumu
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847731/
https://ncbi.nlm.nih.gov/pubmed/26982728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17172
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