Oxidized LDL signals through Rho-GTPase to induce endothelial cell stiffening and promote capillary formation

Endothelial biomechanics is emerging as a key factor in endothelial function. Here, we address the mechanisms of endothelial stiffening induced by oxidized LDL (oxLDL) and investigate the role of oxLDL in lumen formation. We show that oxLDL-induced endothelial stiffening is mediated by CD36-dependen...

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Dades bibliogràfiques
Publicat a:J Lipid Res
Autors principals: Oh, Myung-Jin, Zhang, Chongxu, LeMaster, Elizabeth, Adamos, Crystal, Berdyshev, Evgeny, Bogachkov, Yedida, Kohler, Erin E., Baruah, Jugajyoti, Fang, Yun, Schraufnagel, Dean E., Wary, Kishore K., Levitan, Irena
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2016
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847627/
https://ncbi.nlm.nih.gov/pubmed/26989083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M062539
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