Oxidized LDL signals through Rho-GTPase to induce endothelial cell stiffening and promote capillary formation

Endothelial biomechanics is emerging as a key factor in endothelial function. Here, we address the mechanisms of endothelial stiffening induced by oxidized LDL (oxLDL) and investigate the role of oxLDL in lumen formation. We show that oxLDL-induced endothelial stiffening is mediated by CD36-dependen...

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Detalles Bibliográficos
Publicado en:J Lipid Res
Main Authors: Oh, Myung-Jin, Zhang, Chongxu, LeMaster, Elizabeth, Adamos, Crystal, Berdyshev, Evgeny, Bogachkov, Yedida, Kohler, Erin E., Baruah, Jugajyoti, Fang, Yun, Schraufnagel, Dean E., Wary, Kishore K., Levitan, Irena
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Research Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847627/
https://ncbi.nlm.nih.gov/pubmed/26989083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M062539
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