Oxidized LDL signals through Rho-GTPase to induce endothelial cell stiffening and promote capillary formation

Endothelial biomechanics is emerging as a key factor in endothelial function. Here, we address the mechanisms of endothelial stiffening induced by oxidized LDL (oxLDL) and investigate the role of oxLDL in lumen formation. We show that oxLDL-induced endothelial stiffening is mediated by CD36-dependen...

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Bibliografiska uppgifter
I publikationen:J Lipid Res
Huvudupphovsmän: Oh, Myung-Jin, Zhang, Chongxu, LeMaster, Elizabeth, Adamos, Crystal, Berdyshev, Evgeny, Bogachkov, Yedida, Kohler, Erin E., Baruah, Jugajyoti, Fang, Yun, Schraufnagel, Dean E., Wary, Kishore K., Levitan, Irena
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Biochemistry and Molecular Biology 2016
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847627/
https://ncbi.nlm.nih.gov/pubmed/26989083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M062539
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