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Mutations in Cockayne Syndrome-Associated Genes (Csa and Csb) Predispose to Cisplatin-Induced Hearing Loss in Mice

Cisplatin is a common and effective chemotherapeutic agent, yet it often causes permanent hearing loss as a result of sensory hair cell death. The causes of sensitivity to DNA-damaging agents in nondividing cell populations, such as cochlear hair and supporting cells, are poorly understood, as are t...

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Podrobná bibliografie
Vydáno v:J Neurosci
Hlavní autoři: Rainey, Robert N., Ng, Sum-yan, Llamas, Juan, van der Horst, Gijsbertus T. J., Segil, Neil
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846672/
https://ncbi.nlm.nih.gov/pubmed/27122034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3890-15.2016
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