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Online flow cytometry for monitoring apoptosis in mammalian cell cultures as an application for process analytical technology
Apoptosis is the main driver of cell death in bioreactor suspension cell cultures during the production of biopharmaceuticals from animal cell lines. It is known that apoptosis also has an effect on the quality and quantity of the expressed recombinant protein. This has raised the importance of stud...
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| Published in: | Cytotechnology |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer Netherlands
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4846633/ https://ncbi.nlm.nih.gov/pubmed/25352493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-014-9791-3 |
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