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Online flow cytometry for monitoring apoptosis in mammalian cell cultures as an application for process analytical technology

Apoptosis is the main driver of cell death in bioreactor suspension cell cultures during the production of biopharmaceuticals from animal cell lines. It is known that apoptosis also has an effect on the quality and quantity of the expressed recombinant protein. This has raised the importance of stud...

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Vydáno v:Cytotechnology
Hlavní autoři: Kuystermans, Darrin, Avesh, Mohd, Al-Rubeai, Mohamed
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Netherlands 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846633/
https://ncbi.nlm.nih.gov/pubmed/25352493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-014-9791-3
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