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Online flow cytometry for monitoring apoptosis in mammalian cell cultures as an application for process analytical technology

Apoptosis is the main driver of cell death in bioreactor suspension cell cultures during the production of biopharmaceuticals from animal cell lines. It is known that apoptosis also has an effect on the quality and quantity of the expressed recombinant protein. This has raised the importance of stud...

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Bibliografski detalji
Izdano u:Cytotechnology
Glavni autori: Kuystermans, Darrin, Avesh, Mohd, Al-Rubeai, Mohamed
Format: Artigo
Jezik:Inglês
Izdano: Springer Netherlands 2014
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846633/
https://ncbi.nlm.nih.gov/pubmed/25352493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-014-9791-3
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