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Online flow cytometry for monitoring apoptosis in mammalian cell cultures as an application for process analytical technology

Apoptosis is the main driver of cell death in bioreactor suspension cell cultures during the production of biopharmaceuticals from animal cell lines. It is known that apoptosis also has an effect on the quality and quantity of the expressed recombinant protein. This has raised the importance of stud...

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Detalhes bibliográficos
Publicado no:Cytotechnology
Main Authors: Kuystermans, Darrin, Avesh, Mohd, Al-Rubeai, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846633/
https://ncbi.nlm.nih.gov/pubmed/25352493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-014-9791-3
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