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The p21-activated kinase, PAK2, is important in the activation of numerous pancreatic acinar cell signaling cascades and in the onset of early pancreatitis events

In a recent study we explored Group-1-p21-activated kinases(GP.1-PAKs) in rat pancreatic acini. Only PAK2 was present; it was activated by gastrointestinal-hormones/neurotransmitters and growth factors in a PKC-,Src- and small-GTPases-mediated manner. PAK2 was required for enzyme-secretion and ERK/1...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Biochim Biophys Acta
मुख्य लेखकों: Nuche-Berenguer, Bernardo, Ramos-Álvarez, Irene, Jensen, R. T.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2016
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4846574/
https://ncbi.nlm.nih.gov/pubmed/26912410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2016.02.008
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