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P21-activated kinase 4 in pancreatic acinar cells is activated by numerous gastrointestinal hormones/neurotransmitters and growth factors by novel signaling, and its activation stimulates secretory/growth cascades

p21-activated kinases (PAKs) are highly conserved serine/threonine protein kinases, which are divided into two groups: group-I (PAKs1–3) and group-II (PAKs4–6). In various tissues, Group-II PAKs play important roles in cytoskeletal dynamics and cell growth as well as neoplastic development/progressi...

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Bibliografische gegevens
Gepubliceerd in:Am J Physiol Gastrointest Liver Physiol
Hoofdauteurs: Ramos-Alvarez, Irene, Jensen, R. T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6139648/
https://ncbi.nlm.nih.gov/pubmed/29672153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00005.2018
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