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The p21-activated kinase, PAK2, is important in the activation of numerous pancreatic acinar cell signaling cascades and in the onset of early pancreatitis events
In a recent study we explored Group-1-p21-activated kinases(GP.1-PAKs) in rat pancreatic acini. Only PAK2 was present; it was activated by gastrointestinal-hormones/neurotransmitters and growth factors in a PKC-,Src- and small-GTPases-mediated manner. PAK2 was required for enzyme-secretion and ERK/1...
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| Publicado no: | Biochim Biophys Acta |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4846574/ https://ncbi.nlm.nih.gov/pubmed/26912410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2016.02.008 |
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