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RSK3 is required for concentric myocyte hypertrophy in an activated Raf1 model for Noonan syndrome
Noonan syndrome (NS) is a congenital disorder resulting from mutations of the Ras-Raf signaling pathway. Hypertrophic cardiomyopathy associated with RAF1 “RASopathy” mutations is a major risk factor for heart failure and death in NS and has been attributed to activation of MEK1/2-ERK1/2 mitogen-acti...
Gorde:
| Argitaratua izan da: | J Mol Cell Cardiol |
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| Egile Nagusiak: | , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
2016
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4846495/ https://ncbi.nlm.nih.gov/pubmed/26940993 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2016.02.020 |
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